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Exploiting mitochondria as targets for the development of new antifungals

Large-scale randomized controlled trials are urgently needed to establish safe lipid thresholds and optimize therapeutic strategies

Complement complexes can be discovered in atherosclerotic lesions, and ECs exposed to complement are activated and improves the production of IL-6, IL-8 and MCP-1, thereby triggering the adhesion of monocytes to ECs 89

It was found that a 23-fold -synuclein overexpression in hippocampal and ventral midbrain neurons impeded synaptic vesicle release [116] while -synuclein knock-out mice displayed stronger release of DA upon stimulus [117]